guiDesigner has a built in auto save feature.
Every 10 minutes guiDesigner automatically creates an autosave file. This process creates an .asv file in the same directory as your saved .gui file.
If you need to load the autosave file, simply change the file extension from .asv to .gui and open it with guiDesigner.
This is helpful in case you have a corrupt or damaged file that causes guiDesigner to crash.